Quinolines-1,2,3-triazolylcarboxamides exhibits antiparasitic activity in Trichomonas vaginalis
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چکیده
منابع مشابه
Hydrogenosome metabolism is the key target for 1 antiparasitic activity of resveratrol against 2 Trichomonas vaginalis
Corresponding author 13 Laboratorio de Parasitología, 14 Instituto de Investigación y Análisis Alimentarios, 15 c/ Constantino Candeira s/n, 16 15782, Santiago de Compostela (La Coruña), Spain 17 Tel: +34 981 56 31 00 18 Fax: + 34 881 81 60 27 19 E-mail address: [email protected] 20 21 Copyright © 2013, American Society for Microbiology. All Rights Reserved. Antimicrob. Agents Chemother. ...
متن کاملHydrogenosome metabolism is the key target for antiparasitic activity of resveratrol against Trichomonas vaginalis.
Metronidazole (MDZ) and related 5-nitroimidazoles are the recommended drugs for treatment of trichomoniasis, a sexually transmitted disease caused by the protozoan parasite Trichomonas vaginalis. However, novel treatment options are needed, as recent reports have claimed resistance to these drugs in T. vaginalis isolates. In this study, we analyzed for the first time the in vitro effects of the...
متن کاملTrichomonas vaginalis
We have investigated the effects of a novel neutrophil-activating factor released by Trichomonas vaginalis (TV-NAF) on neutrophil chemotaxis. TV-NAF was present in the supernatant from 107 T. vaginalis (STV) cultured in 1 ml of serum-free Hanks' balanced salt solution (HBSS) at 37°C for 30 min. With a multichamber chemotactic assay, we found that there were 112 + 15 migrated neutrophils (mean ±...
متن کاملPrevalence of Trichomonas Vaginalis in Diabetic Females
Abstract Background and Objective: Trichomonas vaginalis is a pathogenic agent known worldwide and affects about 180 million annually. We aimed to investigate the prevalence of Trichomonas vaginalis in diabetic patients referred to diabetic research center. Material and Methods: In this descriptive-analytic study, 215 women referring to the Diabetic Center in Kermanshah Province were invest...
متن کاملTrichomonas vaginalis in Pregnancy
Pregnancy Trichomonas vaginalis is a common cause of vaginitis in both the pregnant and nonpregnant patient. This protozoan is usually susceptible to metronidazole, but there is reluctance to administer this antibiotic to pregnant patients. The presence of T. vaginalis usually indicates that the vaginal ecosystem has become unbalanced. The microflora tends to shift from a lactobacilli-dominant ...
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ژورنال
عنوان ژورنال: Biotechnology Research and Innovation
سال: 2019
ISSN: 2452-0721
DOI: 10.1016/j.biori.2019.06.003